Capecitabine-induced Leukoencephalopathy
نویسندگان
چکیده
منابع مشابه
Capecitabine-induced leukoencephalopathy involving the bilateral corticospinal tracts.
An 80 year old lady with a history of metastatic sigmoid carcinoma presented with expressive dysphasia and unsteady gait 4 days after commencement of adjuvant capecitabine chemotherapy. MRI demonstrated restricted diffusion and T2/FLAIR hyperintensity involving the course of the bilateral corticospinal tracts, the corpus callosum and the middle cerebellar peduncles. Discontinuation of chemother...
متن کاملCapecitabine-Induced Coronary Vasospasm
Capecitabine, an oral prodrug of 5-fluorouracil (5-FU), is approved for early-stage and advanced colorectal cancer and metastatic breast cancer. Cardiotoxicity of 5-FU is well described in the literature. However, cardiac adverse effects of capecitabine are poorly described. We report a case of coronary vasospasm induced by capecitabine. A 41-year-old female with metastatic breast cancer presen...
متن کاملTeaching NeuroImages: 5-FU-induced acute leukoencephalopathy.
A 55-year-old man with carcinoma sigmoid colon (fluorouracil [5-FU]: cumulative dose of 6,600 mg/m; and oxaliplatinum: 245 mg/m) presented with encephalopathy and pancerebellar involvement 2 weeks after receiving a third cycle of chemotherapy. Brain MRI showed diffusion restriction in bilateral deep white matter, cerebellar peduncles, and splenium of corpus callosum (figures 1 and 2) suggestive...
متن کاملLinezolid-induced posterior reversible leukoencephalopathy syndrome.
OBJECTIVE To describe a 71-year-old woman who developed clinical and neuroradiological features of posterior reversible leukoencephalopathy syndrome with a compromised blood-brain barrier after 5 days of intravenous linezolid therapy for an infected hip prosthesis. DESIGN Case report. SETTING Academic research. MAIN OUTCOME MEASURES Posterior reversible leukoencephalopathy syndrome was do...
متن کاملReversible severe fatty liver induced by capecitabine
RATIONALE Capecitabine (CAP) is a chemotherapeutic agent used to treat breast and gastrointestinal cancers. The most common adverse reactions of CAP primarily included gastrointestinal and dermatological effects. Whereas, the CAP-induced fatty liver had never been reported. PATIENT CONCERNS In this study, a-69-year old female presented a history of hypertension with regulated blood pressure, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Internal Medicine
سال: 2019
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.0961-18